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Hong Yuan Selected Research

Oxazolidinones (2 Oxazolidone)

1/2022A Phase III multicentre, randomized, double-blind trial to evaluate the efficacy and safety of oral contezolid versus linezolid in adults with complicated skin and soft tissue infections.
10/2021Pharmacokinetics and Disposition of Contezolid in Humans: Resolution of a Disproportionate Human Metabolite for Clinical Development.
1/2020Evaluation of the Effect of Contezolid (MRX-I) on the Corrected QT Interval in a Randomized, Double-Blind, Placebo- and Positive-Controlled Crossover Study in Healthy Chinese Volunteers.
1/2019Tolerability and Pharmacokinetics of Contezolid at Therapeutic and Supratherapeutic Doses in Healthy Chinese Subjects, and Assessment of Contezolid Dosing Regimens Based on Pharmacokinetic/Pharmacodynamic Analysis.

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Hong Yuan Research Topics

Disease

161Neoplasms (Cancer)
07/2022 - 06/2005
23Breast Neoplasms (Breast Cancer)
07/2022 - 09/2008
22Hypertension (High Blood Pressure)
11/2021 - 10/2011
17Neoplasm Metastasis (Metastasis)
06/2022 - 01/2013
17Infections
01/2022 - 02/2013
12Inflammation (Inflammations)
07/2021 - 05/2005
10Hypoxia (Hypoxemia)
06/2022 - 06/2005
8Ovarian Neoplasms (Ovarian Cancer)
01/2019 - 09/2008
7Pain (Aches)
07/2022 - 10/2010
7Hepatocellular Carcinoma (Hepatoma)
06/2022 - 01/2011
7Essential Hypertension
01/2021 - 07/2013
6Colorectal Neoplasms (Colorectal Cancer)
05/2022 - 09/2016
6Cardiovascular Diseases (Cardiovascular Disease)
01/2018 - 03/2013
5Diabetes Mellitus
11/2022 - 12/2009
5Prostatic Neoplasms (Prostate Cancer)
04/2022 - 01/2013
5Atherosclerosis
10/2021 - 09/2018
5Osteoporosis
10/2021 - 01/2015
5Non-alcoholic Fatty Liver Disease
12/2020 - 12/2016
5Brain Neoplasms (Brain Tumor)
11/2017 - 11/2013
5Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung)
01/2017 - 07/2012
5Parkinson Disease (Parkinson's Disease)
02/2010 - 11/2004
4Chronic Renal Insufficiency
11/2022 - 01/2014
4Lung Neoplasms (Lung Cancer)
03/2021 - 10/2013
4Abdominal Obesity
01/2021 - 12/2013
4Coronary Disease (Coronary Heart Disease)
01/2021 - 12/2009
4Glioma (Gliomas)
08/2020 - 01/2012
4Glioblastoma (Glioblastoma Multiforme)
01/2020 - 09/2015
4Bites and Stings (Sting)
01/2020 - 01/2016
4Type 2 Diabetes Mellitus (MODY)
01/2019 - 12/2013
4Insulin Resistance
01/2018 - 11/2010
4Carcinoma (Carcinomatosis)
09/2016 - 01/2009
3Pathologic Processes
06/2022 - 01/2011
3Body Weight (Weight, Body)
01/2022 - 09/2008
3Stroke (Strokes)
01/2022 - 01/2018
3Ulcerative Colitis
01/2022 - 02/2020

Drug/Important Bio-Agent (IBA)

47Pharmaceutical PreparationsIBA
07/2022 - 06/2006
42MicellesIBA
06/2022 - 08/2007
23Doxorubicin (Adriamycin)FDA LinkGeneric
01/2022 - 09/2008
21ChitosanIBA
06/2022 - 01/2008
20GlycolipidsIBA
06/2021 - 02/2009
19LipidsIBA
10/2021 - 09/2008
16Proteins (Proteins, Gene)FDA Link
01/2022 - 12/2008
14Peptides (Polypeptides)IBA
06/2016 - 11/2006
13Paclitaxel (Taxol)FDA LinkGeneric
01/2020 - 12/2007
11PolymersIBA
06/2021 - 01/2008
11Biomarkers (Surrogate Marker)IBA
08/2020 - 04/2011
10Calcium Carbonate (Limestone)FDA Link
10/2021 - 03/2017
10Glucose (Dextrose)FDA LinkGeneric
01/2020 - 06/2005
9Therapeutic UsesIBA
03/2021 - 09/2004
8Uric Acid (Urate)IBA
10/2021 - 01/2013
8CytokinesIBA
10/2021 - 01/2015
8OligosaccharidesIBA
01/2017 - 01/2008
7Small Interfering RNA (siRNA)IBA
01/2022 - 11/2011
7Lipid NanoparticlesIBA
11/2020 - 02/2008
7stearic acid (magnesium stearate)FDA LinkGeneric
01/2017 - 01/2008
6LigandsIBA
11/2020 - 01/2011
6SolutionsIBA
01/2020 - 01/2011
5Biological ProductsIBA
06/2022 - 02/2014
5contezolidIBA
01/2022 - 01/2019
5RNA (Ribonucleic Acid)IBA
10/2021 - 10/2019
5Antihypertensive Agents (Antihypertensives)IBA
10/2021 - 07/2013
5CalciumIBA
10/2021 - 02/2010
5Long Noncoding RNAIBA
08/2021 - 11/2016
5Triglycerides (Triacylglycerol)IBA
01/2021 - 10/2013
5Messenger RNA (mRNA)IBA
01/2021 - 11/2011
5Phospholipids (Phosphatides)FDA LinkGeneric
01/2021 - 11/2018
5IntegrinsIBA
10/2020 - 01/2011
5Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA
01/2020 - 07/2013
5ORALIT (ORS)IBA
06/2018 - 01/2015
5DNA (Deoxyribonucleic Acid)IBA
01/2016 - 12/2011
4oxidized low density lipoproteinIBA
01/2022 - 01/2019
4Contrast MediaIBA
01/2022 - 01/2009
4Oxazolidinones (2 Oxazolidone)IBA
01/2022 - 01/2019
4EnzymesIBA
10/2021 - 01/2017
4Simvastatin (Zocor)FDA LinkGeneric
10/2021 - 01/2015
4Oxygen (Dioxygen)IBA
01/2021 - 06/2005
4Metoprolol (Toprol-XL)FDA LinkGeneric
01/2021 - 10/2011
41-phenyl-3,3-dimethyltriazene (PDT)IBA
01/2021 - 01/2020
4Hemoglobins (Hemoglobin)IBA
05/2020 - 01/2013
4HDL CholesterolIBA
01/2020 - 04/2015
4cyclic guanosine monophosphate-adenosine monophosphateIBA
01/2020 - 01/2016
4Drug CarriersIBA
11/2019 - 01/2011
4MicroRNAs (MicroRNA)IBA
09/2019 - 01/2014
4Phosphotransferases (Kinase)IBA
10/2018 - 11/2010
4HMGB1 Protein (HMG1)IBA
08/2017 - 09/2015
3Lactic Acid (Lactate)FDA LinkGeneric
06/2022 - 06/2005
3Folic Acid (Vitamin M)FDA LinkGeneric
06/2022 - 01/2008
3AndrogensIBA
04/2022 - 01/2013
3CreatinineIBA
01/2022 - 01/2013
3Blood Glucose (Blood Sugar)IBA
01/2022 - 01/2016
3Anti-Bacterial Agents (Antibiotics)IBA
01/2022 - 01/2020

Therapy/Procedure

76Therapeutics
06/2022 - 11/2008
23Drug Therapy (Chemotherapy)
01/2022 - 12/2007
18Radiotherapy
03/2021 - 11/2006
9Lasers (Laser)
01/2020 - 06/2013
7Immunotherapy
10/2021 - 01/2016
7Aftercare (After-Treatment)
09/2018 - 12/2008
5Precision Medicine
06/2022 - 11/2015
4Photochemotherapy (Photodynamic Therapy)
12/2021 - 01/2020
4Photothermal Therapy
01/2021 - 03/2015